A recent study published in the journal Cell has strengthened the hypothesis that the COVID-19 pandemic may have originated from infected animals sold at a market in Wuhan, China, rather than from a laboratory leak.
The research team, which includes scientists from the US and France, analyzed hundreds of environmental samples collected from the Huanan Seafood Wholesale Market in January 2020.
The findings suggest that several animals, including raccoon dogs, civets, and bamboo rats, could have been potential sources of the virus. Notably, the analysis identified a specific stall in the market as a hotspot for both animal genetic material and the coronavirus, although definitive proof of animal infection has not been established.
The study builds on earlier research conducted by Chinese officials, who swabbed various surfaces in the market shortly after it was closed due to the outbreak. The raw data from that investigation was made publicly available, allowing further analysis by the current research team. They employed advanced genetic techniques to examine millions of DNA and RNA fragments, discovering a correlation between the presence of susceptible animals and the virus in certain market areas.
“We are seeing the DNA and RNA ghosts of these animals in the environmental samples, and some are in stalls where the Covid virus was found too,” stated Prof. Florence Débarre, a co-author of the study.
Prof. Kristian Andersen added that the results suggest a strong link between the market and the early spread of COVID-19.
Despite these findings, the research acknowledges limitations. The samples collected cannot confirm whether any animals were infected with the virus, as the swabs were taken after the animals had been removed from the market. Furthermore, the analysis cannot definitively rule out the possibility that humans introduced the virus to the market.
The study suggests that COVID-19 may have emerged from multiple spillover events involving animals at the market, reinforcing the idea that it was the epicenter of the outbreak. However, it remains a contentious topic, as alternative theories, including the lab-leak hypothesis, continue to circulate.
Experts caution that while the evidence leans toward a natural origin, the complexities surrounding the pandemic’s beginnings mean that definitive conclusions remain elusive.
BBC, the Washington Post, Newsweek, and the Hill contributed to this report.