Environment Health Science USA

Alarming Discovery: Microplastics Are Accumulating in Human Brains, Raising Concerns About Potential Health Risks

Alarming Discovery: Microplastics Are Accumulating in Human Brains, Raising Concerns About Potential Health Risks
Leonard Ortiz / MediaNews Group / Orange County Register via Getty Images
  • PublishedFebruary 9, 2025

Recent research has revealed a disturbing trend: microplastics are increasingly accumulating in human brains, with concentrations rising by 50% over the past eight years.

Microplastics—tiny fragments of plastic—have long been recognized as a widespread environmental contaminant, but new findings from the University of New Mexico Health Sciences suggest that the particles may pose a serious health risk, potentially affecting brain function and contributing to conditions like dementia.

Microplastics have already been detected in a variety of human organs, including the liver, kidneys, and placenta. However, the recent study led by Dr. Matthew Campen, a toxicologist at the University of New Mexico, marks the first time these particles have been found in the brain in significant concentrations. The research, published in Nature Medicine, reveals that plastic accumulation in the brain is higher than in other organs and is steadily increasing over time.

Microplastics are small fragments, often no larger than 200 nanometers, that are created as larger pieces of plastic degrade in the environment. These particles are pervasive, found in air, water, and soil, and enter the human body primarily through food, particularly meat, which accumulates plastics from contaminated water and feed.

The new study used an innovative method to analyze brain tissue samples from people who had passed away. These samples were collected from the frontal cortex—the brain region involved in decision-making and memory. Researchers found plastic concentrations in the brain to be higher than in the liver or kidneys, and the amount of plastic in brain tissue had increased by 50% over an eight-year period.

One of the most concerning findings of the study was the discovery of plastic fragments on the nanometer scale—particles so small they are capable of crossing the blood-brain barrier, which typically protects the brain from harmful substances.

Researchers found that brain tissue from individuals diagnosed with dementia contained up to ten times more microplastic than the general population. While there is a clear correlation between higher plastic concentrations and dementia, it remains unclear whether the plastics are causing the disease or simply accumulating more in those already affected by the condition.

Dr. Campen suggested that these particles could obstruct blood flow in capillaries, interfere with the connections between brain cells, or even contribute to protein aggregation, which is associated with neurodegenerative diseases. However, more research is needed to understand the exact impact of microplastics on brain health.

The study underscores a growing environmental crisis. Despite ongoing efforts to reduce plastic production, plastic waste continues to accumulate globally, and the particles break down into smaller and smaller pieces, eventually reaching the microscopic level. If plastic production were to cease tomorrow, the existing plastic waste would continue to degrade into microplastics for decades.

The implications for human health are still being studied, but the evidence so far suggests that these particles may be contributing to a range of health issues, including respiratory problems, organ damage, and now, potentially, brain disorders like dementia.

Dr. Campen has called for greater awareness of this issue, highlighting that people are generally unaware of the plastic accumulating in their bodies. He believes that more research and regulatory action are needed to understand and mitigate the risks of microplastics.

SciTechDaily and Salon contributed to this report.